Music · Medicine · BrainAll chapters

CHAPTER 18 · Music’s Neurological Nexus in Clinical Practice

Music-Based Interventions for Neurocognitive Disorders

Borna Bonakdarpour, MD, FAAN, FANA · Clara Takarabe, CMP

ABOUT THE AUTHORS

Abstract

As discussed in this chapter, music can influence and modulate multiple brain networks, affecting emotions, motor, speech/language, navigation, executive function, and memory, based on principles of neuroplasticity and neurorehabilitation. We discuss how music as an intervention for dementia has been used since the mid-20th century and is now an important role in the care of persons with neurocognitive disorders. More robust research, however, is needed to prove its power and integration into standard care and foster insurance reimbursement. Music-based interventions, categorized as expressive and receptive, are utilized for non-fluent aphasias and dementia. Specific approaches include playlists, individualized receptive interventions, interactive music-making, and choral singing. Given our better understanding and awareness of music-based Interventions, future work in this area will focus on a better understanding of the mechanisms of action and providing stronger evidence of their efficacy using large-scale controlled clinical trials.

Keywords

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Cite this chapter

Chapter references below omit unverified page ranges and chapter-specific DOIs.

APA

Bonakdarpour, B., & Takarabe, C. (2026). Music-Based Interventions for Neurocognitive Disorders. In P. L. Pearl & S. Arfaie (Eds.), Music, Medicine, and the Neurobiology of Creativity. Cambridge University Press.

AMA

Bonakdarpour B, Takarabe C. Music-Based Interventions for Neurocognitive Disorders. In: Pearl PL, Arfaie S, eds. Music, Medicine, and the Neurobiology of Creativity. Cambridge University Press; 2026.

Vancouver

Bonakdarpour B, Takarabe C. Music-Based Interventions for Neurocognitive Disorders. In: Pearl PL, Arfaie S, editors. Music, Medicine, and the Neurobiology of Creativity. Cambridge: Cambridge University Press; 2026.

Chicago

Bonakdarpour, Borna, and Clara Takarabe. “Music-Based Interventions for Neurocognitive Disorders.” In Music, Medicine, and the Neurobiology of Creativity, edited by Phillip L. Pearl and Saman Arfaie. Cambridge University Press, 2026.

BibTeX

@incollection{chapter18_2026,
  author = {Bonakdarpour, Borna and Takarabe, Clara},
  title = {Music-Based Interventions for Neurocognitive Disorders},
  booktitle = {Music, Medicine, and the Neurobiology of Creativity},
  editor = {Pearl, Phillip L. and Arfaie, Saman},
  publisher = {Cambridge University Press},
  year = {2026}
}

Harvard

Bonakdarpour, B. and Takarabe, C. (2026) “Music-Based Interventions for Neurocognitive Disorders”, in Pearl, P.L. and Arfaie, S. (eds.) Music, Medicine, and the Neurobiology of Creativity. Cambridge: Cambridge University Press.

Borna Bonakdarpour

Borna Bonakdarpour

MD, FAAN, FANA

Associate Professor of Neurology; Northwestern Music and Medicine Program

Northwestern University

Profile

Borna Bonakdarpour is an Associate Professor of Neurology at Northwestern University Feinberg School of Medicine and is affiliated with its Music and Medicine Program and Mesulam Center for Cognitive Neurology and Alzheimer’s Disease. His contributions with Clara Takarabe address music-based interventions for neurocognitive disorders and the early connections among music, medicine, and neuroscience in Plato’s Laws and Republic.

Scholarship & professional background

His work brings cognitive neurology into dialogue with musical practice, including his own background as a pianist. With Clara Takarabe, he co-founded Northwestern’s Music and Medicine Program, which investigates and delivers music-based approaches in clinical settings. Their research includes a pilot study of live improvisatory viola music for people undergoing epilepsy monitoring. His broader work addresses language and cognitive disorders and the potential role of structured musical experiences in the lives of people with dementia.

In September 2026, Northwestern reported his work with Clara Takarabe on restorative improvisatory music for healthcare workers. The study used participant surveys to examine emotional state and energy following brief listening sessions, extending their clinical music research to clinician wellbeing.

Selected work & perspectives

Music, cognition, and clinical neuroscienceMusic and Medicine Program · Northwestern UniversityImprovisatory music during epilepsy monitoringRestorative music and clinician wellbeing · September 2026
Clara Takarabe

Clara Takarabe

CMP

Clinical Music Practitioner, Northwestern Music and Medicine Program

Northwestern University

Profile

Clara Takarabe is a clinical music practitioner affiliated with Northwestern University’s Music and Medicine Program and Mesulam Center for Cognitive Neurology and Alzheimer’s Disease. Her chapters with Borna Bonakdarpour connect music-based interventions for neurocognitive disorders with an examination of music, medicine, and neuroscience in Plato’s Laws and Republic.

Scholarship & professional background

Her background combines philosophy, professional viola performance, and clinical music practice. She has performed with the Chicago Symphony Orchestra and co-directs Northwestern’s Music and Medicine Program with Borna Bonakdarpour. Their work includes investigating live, improvisatory music in clinical settings, including a pilot study during epilepsy monitoring. This approach brings the responsiveness of a performing musician into close contact with questions about attention, distress, and neurological experience.

Her recent work includes co-developing and providing music for a healthcare-worker wellbeing intervention studied at Northwestern. Published in September 2026, the project examined self-reported responses to short sessions of live or recorded restorative improvisatory music, including her viola recordings.

Selected work & perspectives

Academic profile and professional workMusic, philosophy, and clinical practice · UCSFMusic and Medicine Program · Northwestern UniversityMusic for healthcare-worker wellbeing · September 2026